modafinil will lessen the level or impact of mavacamten by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
modafinil will improve the amount or outcome of pantoprazole by affecting hepatic enzyme CYP2C19 metabolism. Minimal/Significance Not known. Web effect on pantoprazole actions not known as a result of opposing consequences of CYP450 enzymes; keep track of
Modafinil Tablets, USP 100mg–White to off white capsule shaped uncoated tablets debossed with AC 132 on 1 aspect and simple on other side. Modafinil Tablets, USP two hundred mg – White to off white spherical shaped uncoated pill scored around the a person side with AC higher than and 133 underneath and plain on other facet.
ribociclib will increase the level or result of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
nevirapine will reduce the extent or influence of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
Indicated to further improve wakefulness in Older people with abnormal sleepiness linked to obstructive snooze apnea (OSA)
Nearly all medication that enter the body are metabolized via the liver. The liver works by using a set of enzymes to stop working chemicals. Every one is coded by a specific gene, which we seek advice from as being the CYP450 isoenzymes.
In determining to implement a medication, the hazards of using the medication must be weighed towards The great it's going to do. This is a choice both you and your medical doctor could make. For this medicine, the subsequent need to be thought of:
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Hazard of pores and skin reactions (eg SJS, toxic necrolysis, and drug rash with eosinophilia and systemic signs and symptoms); discontinue if rash or other hypersensitivity reactions happen
For that reason, coadministration of ozanimod with medicine which can increase norepinephrine or serotonin is just not advised. Check for hypertension with concomitant use.
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fosphenytoin will reduce the level or outcome of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.